There are very few reports of bone marrow hyperplasia with cancer; therefore, we have the potential to misdiagnose bone marrow hyperplasia as bone metastases when not diagnosed carefully. Bone marrow hyperplasia is a marrow reconversion that refers to repopulating yellow marrow to red marrow.
What is the meaning of marrow hyperplasia?
Definition. Increase in the number of hematopoietic cells in the bone marrow. It may involve all or individual hematopoietic cell lines. [
What happens in bone marrow hyperplasia?
The bone marrow hyperplasia has the resultant effect of weakening the skeletal tissue by widening the medullary cavities, replacing trabecular bone and thinning cortices.
Is bone marrow cancer the same as leukemia?
Bone marrow is a soft, spongy tissue that is in the center of most bones. Several types of cancer, including multiple myeloma, leukemia, and lymphoma, can develop in the bone marrow.
What causes bone marrow hyperplasia?
Hemorrhage, hemolytic anemia, intrinsic bone marrow disease (including aplastic anemia or malignancies), and anemia of chronic disease are the most common causes of erythroid hyperplasia associated with normocytic anemia in patients with no history of a toxic insult, chemotherapy, or hemoglobinopathy.
Is Hypercellular bone marrow bad?
An important feature of a bone marrow sample is how much of it is blood-forming cells. This is known as cellularity. Normal bone marrow contains both blood-forming cells and fat cells. If your bone marrow has more blood-forming cells than expected, its said to be hypercellular.
What causes Hypercellular bone marrow?
Chromosomal abnormalities (eg, deletions, duplications, structural abnormalities) are often present. The bone marrow can be hypocellular or hypercellular. The ineffective hematopoiesis causes anemia (most common), neutropenia, thrombocytopenia, or a combination of these, even to the point of marrow aplasia.
Is bone marrow cancer curable?
In some cases, a bone marrow or stem cell transplant is an option. Multiple myeloma isnt considered “curable,” but symptoms wax and wane. There can be a long period of dormancy that could last several years. However, this cancer usually recurs.