This medication may rarely cause gallstones and liver problems. If you notice any of the following unlikely but serious side effects, tell your doctor right away: persistent nausea/vomiting, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.
What are the side effects of the drug fenofibrate?
The more common side effects that can occur with use of fenofibrate include:headache.back pain.nausea.indigestion.stuffy or runny nose.stomach pain.
Should fenofibrate be taken at night?
Some people find it helps to swallow the tablet/capsule with a drink of water. You can generally take fenofibrate at a time of day to suit you, but it is best to take your doses with the same meal each day.
How long can you take fenofibrate?
Monitoring of cholesterol/triglyceride levels every four to eight weeks is important to establish the effectiveness of fenofibrate therapy. Your doctor should consider discontinuing therapy if you have not had an adequate response after two months of treatment.
What is fenofibrate used for?
Fenofibrate is used with a low-fat diet, exercise, and sometimes with other medications to reduce the amounts of fatty substances such as cholesterol and triglycerides in the blood and to increase the amount of HDL (high-density lipoprotein; a type of fatty substance that decreases the risk of heart disease) in the ...
Will I lose weight taking fenofibrate?
Dietary fenofibrate (100 mg/kg per day) also reduced the food intake, body weight, and adiposity of obese Otsuka Long-Evans Tokushima Fatty (OLETF) rats . In db/db mice, fenofibrate (0.2%, w/w) treatment was associated with decreased food intake .
Does fenofibrate cause liver damage?
Fenofibrate therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury, which can be severe and prolonged and lead to significant hepatic fibrosis.
Is fenofibrate bad for kidneys?
Results: Most clinical studies showed a rapid (within weeks) raising effect of fenofibrate on SCr levels. This was often accompanied by declined estimated glomerular filtration rate. Risk predictors of this adverse effect might include increased age, impaired renal function and high-dose treatment.
What is the best way to lower triglycerides?
Whats the best way to lower triglycerides?Exercise regularly. Avoid sugar and refined carbohydrates. Lose weight. Choose healthier fats. Trade saturated fat found in meats for healthier fat found in plants, such as olive and canola oils. Limit how much alcohol you drink.
Does fenofibrate make you sleepy?
Check with your doctor right away if you have dark urine, diarrhea, fever, muscle cramps or spasms, muscle pain or stiffness, or feel very tired or weak. These could be symptoms of a serious muscle problem called rhabdomyolysis, which can cause kidney problems. Pancreatitis may occur while you are using this medicine.
Can fenofibrate make you sleepy?
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Is fenofibrate safe for liver?
Conclusions: In patients with non-alcoholic fatty liver disease, treatment with fenofibrate is safe and improves metabolic syndrome, glucose and liver tests.
Can I take fenofibrate in empty stomach?
Background: The main drawback of the lipid-lowering agent fenofibrate is low bioavailability when taken orally on an empty stomach.
Does fenofibrate affect blood pressure?
Fenofibrate, combined therapy, or candesartan all significantly reduced systolic and diastolic blood pressure after 2 months administration when compared with baseline.
Can Walking reduce triglycerides?
When paired with weight loss, studies show that aerobic exercise is especially effective at decreasing triglycerides ( 17 ). The American Heart Association recommends getting at least 30 minutes of aerobic exercise 5 days per week, which can include activities like walking, jogging, bicycling, and swimming (18, 19 ).
Does fenofibrate cause fatty liver?
Experimental studies showed that fenofibrate can limit liver steatosis associated with high-fat diet, T2DM and obesity-related insulin resistance.
Does fenofibrate cause memory loss?
For women but not men, fibrate use was specifically associated with an increased risk over 7 years of decline in visual memory only (HR=1.29, 95%CI=1.09–1.54, p=0.004), and did not increase risk for incident dementia.
Can you take fenofibrate with blood pressure medicine?
RESULTS—Fenofibrate, combined therapy, or candesartan therapy significantly reduced blood pressure. However, combined therapy significantly reduced blood pressure more than fenofibrate or candesartan alone (P < 0.001 by ANOVA).