Alcohol consumers had significantly higher AST and GGT activities compared to non-consumers confirming previous findings demonstrating that alcohol intake is associated with increased hepatic enzyme activities [12, 13].
What effect does alcohol have on enzyme activity?
Most alcohol is broken down, or metabolised, by an enzyme in your liver cells known as alcohol dehydrogenase (ADH). ADH breaks down alcohol into acetaldehyde, and then another enzyme, aldehyde dehydrogenase (ALDH), rapidly breaks down acetaldehyde into acetate.
How does alcohol affect AST and ALT levels?
An elevated serum AST in relation to serum ALT (alanine aminotransferase) has been proposed as an indicator that alcohol has induced organ damage. Thus, when AST/ALT ratio is >1.5, this is considered as highly suggestive that alcohol is the cause of the patients liver injury (Correia et al., 1981; Salaspuro, 1987).
Does alcohol raise liver enzymes?
Alcohol is one of the factors most frequently associated with increased liver enzyme and the association between alcohol intake and alcohol-induced liver disease is well known.
Why cant my body process alcohol?
Alcohol intolerance occurs when your body doesnt have the proper enzymes to break down (metabolize) the toxins in alcohol. This is caused by inherited (genetic) traits most often found in Asians. Other ingredients commonly found in alcoholic beverages, especially in beer or wine, can cause intolerance reactions.